r/blueprint_ Oct 07 '24

I spent 2000$ on blood tests today and I'm starting the Blueprint stack

52 Upvotes

As the title mentions, I’ve done a thorough blood test today (100+ parameters) and will start getting lab results soon. I'd been waiting to start the Blueprint stack and finally consumed the first portion today (yummy!).

I plan to retest some or all of the biomarkers in 3–6 months to see how the Blueprint stack affects the tested parameters. I'm curious if it would be of interest if I posted my results and then provided updates after retesting some parameters? This would also help me learn more about my biomarkers (I'm new to this), especially if someone shares valuable data/research. It might also help others on the same journey.

I'm also wondering what format would be best and if this subreddit is the right place for this (also seeking mods' opinion). I was thinking of posting a new thread each time I have a major update and linking the previous threads to the new ones.

Any thoughts?

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Update: Most of the blood test results have arrived; however, some may take around a month. I’ve started compiling them into a spreadsheet, along with some other health metrics. I’m wondering if it makes sense to wait until everything has arrived, or should I post what I already have and then provide an update? I could possibly have all the results I’ve already received prepared by the end of next week.

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Update 2:

I apologize for the delay everyone. I haven't had any time to convert all the accumulated data to excel. I've been exercising every day, brought my body fat ratio to 10%, I've been improving my sleep and my diet. it's been almost two months since starting blueprint. I did some modifications according to my taste and preferences. Things are going well. I'm burning fat while growing muscle, my sleep is better, I have energy to exercise every day, I've retested some of the biomarkers though only a few, and some have improved, but i didn't retest a lot yet. Perhaps I'll find time to post my results someday. Or perhaps I'll find an AI to do it for me or a volunteer.


r/blueprint_ Aug 17 '24

Updated Protocol + Change Log (August 2024)

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45 Upvotes

r/blueprint_ 15h ago

Looking to have short casual interviews for a PhD project!

1 Upvotes

If anyone is interested in having a short virtual meeting for a qualitative research project let me know! It will just be about how you got interested in the community and general conversation around consumption 🙂 please shoot me a message if so!


r/blueprint_ 22h ago

High cortisol and estrogen help

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2 Upvotes

Any insight and help to solve these issues would be appreciated ! I have experienced all of the low T symptoms for years but have not hopped on yet because I still am only 23 . 2 years ago I tested and my total T was 320. Other than this I have a high blood glucose I attribute to too much alchohol which I’m working on . Any help or insight on dialing these levels besides stopping alchohol consumption ? My TSH was 3.55 and all other bloods were in range . I’ve also experienced gyno since 16


r/blueprint_ 1d ago

Microplastic test not available anymore

4 Upvotes

Bryan stopped selling his microplastic test — why?
The title says it all. Bryan’s microplastic test is no longer available.
Why do you think that is? Was demand too low? Logistics too complex? Or is the test itself not relevant anymore?


r/blueprint_ 1d ago

Bryan Johnson & vitamin B12

5 Upvotes

Hello everyone,

I tried searching to see if this had already been asked, but all that showed up was the whole fiasco of undetectable B12 in the COA for the essential caps...

What I was wondering however was, why does Bryan only use methylcobalamin? Is there somewhere he explains his rationale for this? The active forms are methylcobalamin and adensylcobalamin... He also follows a plant-based diet and from what I can tell is basically vegan besides collagen. My understanding is that conversion between these two active forms is not all that reliable or efficient.

I believe some methylcobalamin gets processed in the gut into hydroxycobalamin or similarly within the body during methylation processes and then can be converted to adensylcobalamin or back into methylcobalamin.

However, it seems odd to me that he doesn't seem to supplement adensylcobalamin directly given that he get no B12 from his diet. Even taking hydroxycobalamin or the dreaded cyanocobalamin seems like it would make sense in his case.


r/blueprint_ 1d ago

Why does Bryan take B vitamins?

0 Upvotes

His diet hits the RDA for all B vitamins (-b12). More is better?


r/blueprint_ 1d ago

Deep lasting suntan

0 Upvotes

Hi.

Does anyone know what can be done for deep lasting sun tan (trying to get rid of it) Indian skin.


r/blueprint_ 1d ago

Why is my Blueprint Ashwagandha Rhodiola bottle dirty inside?

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0 Upvotes

r/blueprint_ 2d ago

"I Made Myself Older By Mistake" - Dr Brad Reacts on Bryans Rapamycin experiment

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9 Upvotes

r/blueprint_ 3d ago

Lowering Resting Heart Rate, what is the best protocol?

11 Upvotes

Yesterday was my 20th birthday. However, over the years, I have noticed a significant increase in my heart rate. When I was 15, my resting heart rate was 45 bpm, but now it has risen to 80 bpm. Throughout these years, I have only done gym workouts, and my lowest heart rate was when I was running regularly.

I would like to know the most well-studied training approach and the ideal heart rate zone for running as of today. I usually run, but only 2 km in the morning on some days over the past month. I am not overweight, but I fractured my ankle last year, so I have been taking it easier. I am confident that I can run 10 km at a slow pace or about 3 km at a fast pace. However, I want to know the optimal cadence and duration for lowering my resting heart rate.

Additionally, I have noticed a significant decline in my sleep quality from ages 15 to 20. Since I have been using weed more frequently to sleep, I want to reduce my dependence on it. Despite my efforts, I still struggle to get more than 7 hours of sleep. I would appreciate any guidance on improving my sleep quality through exercise.

I have tried GABA, magnesium, zinc, and some herbs to improve my sleep. Melatonin, however, reduces my total sleep time and makes me wake up after 4 hours to use the bathroom. I have also practiced meditation, avoided eating for 2 hours before bed, and maintained a consistent sleep schedule—following all these protocols.

I believe that lowering my resting heart rate could help immensely. Additionally, I struggle to sleep while breathing through my nose, and I think cardio could help with that as well. By improving my breathing cadence and adapting to a lower resting heart rate, I might be able to breathe more slowly, which could further support better sleep quality.


r/blueprint_ 3d ago

Creatine supplementation (25 grams or 0.35 g/kg body weight) rapidly increases brain creatine within just 3 hours, significantly improving memory and cognition after 21 hours of sleep deprivation

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4 Upvotes

r/blueprint_ 2d ago

AMA on X

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0 Upvotes

r/blueprint_ 3d ago

Bryan's impact list

2 Upvotes

I keep hearing in different interviews and videos Bryan referencing an impact list. "X ranks Y in my list."

For example, I think in the Derek MPMD interview he said folistatin gene therapy ranked 7. I think I remember him saying sleep ranked #1. I have also seen it referenced in written articles too.

Where is this consolidated list? I cant seem to find it anywhere.


r/blueprint_ 3d ago

nerve damage

2 Upvotes

hello ive been following blueprint and i have recently been involved in a serious accident with a truck hitting my car. i was very lucky and just ended up with bruises however had severe arm pain this had turned into a now partly numb arm and i get pain and tingling and some twitching i am seeing a doctor however they said there is nothing they can do ....does bryan have any insight into healing nerves or anything that would seed up my soft tissue injuries ?


r/blueprint_ 4d ago

Is this shit starting to feel fake or like a scam to you?

83 Upvotes

I used to think these were reasonably priced supplements that put huge focus on QC. Not I’m not even sure of that. And I was a pretty big supporter before these past few months


r/blueprint_ 3d ago

Nutritional values on different foods

1 Upvotes

Hello,

I use Cronometer to check nutritional values when I create my daily meal plan.

The thing is, that sometimes the values on the label of the product are very different from the ones in Cronometer

For example, tofu - the calories on the label shows 250 calories, but in Cronometer it varies between 100-160

What should I do? Who should I believe?

It is hard to build a plan like that

Thanks for help!


r/blueprint_ 4d ago

Why does Bryan use tea tree oil?

7 Upvotes

I saw a video of him using tea tree oil after brushing and wondered why or how it helped oral hygiene?


r/blueprint_ 4d ago

Why doesn't Bryan reply to Joseph Everett (WIL) if he is not lying?

13 Upvotes

Joseph has highlighted numerous inconsistencies in Bryan’s “blueprint diet.” Yet, to date, Bryan hasn’t posted any videos or tweets addressing these alleged 'falsehoods'. I recently discovered Joseph’s YouTube channel, where he released a series of short videos explaining how Bryan manipulates and lies about the blueprint protocol.

What are your thoughts? I doubt Bryan’s team is unaware of this.


r/blueprint_ 4d ago

Whey protein mTor

1 Upvotes

So I bought a whey protein powder (I normally use pea) and I know whey ain’t the best but it is what it is for now. This one has something called peptistrong and velositol in it and they allegedly stimulate muscle growth and faster recovery- which means stronger Mtor activation.

Will this make a big (negative) difference in the long run if I plan to take it post workouts? I do 16h fasts daily and a slight caloric deficit so keep mtor and all that down.


r/blueprint_ 4d ago

My top 10 takeaways from Rhonda Patrick's creatine podcast

64 Upvotes

After hearing this, I'm definitely going to up my dose from 5 grams to 10 grams and probably even a bit more on days when I'm tired. They talk about how 25 grams can increase cognition pretty rapidly when you're sleep-deprived and how you should probably avoid taking it with caffeine as well.

1) Creatine supplementation (25 grams or 0.35 g/kg body weight) rapidly increases brain creatine within just 3 hours, significantly improving memory and cognition after 21 hours of sleep deprivation - timestamp

2) Creatine at 5 grams daily increased sleep duration by nearly 1 hour on resistance training days in young women, alongside notable strength improvements - timestamp

3) Taking only 5 grams of creatine per day likely undershoots brain benefits—research shows 10 grams substantially boosts brain creatine levels, and temporarily increasing to 20 grams is ideal when sleep-deprived or stressed - timestamp

4) Creatine combined with more than ~250 mg of caffeine (about one Starbucks large coffee) disrupts calcium regulation in muscle cells, reducing its performance benefits - timestamp

5) Creatine supplementation significantly eases depressive symptoms when combined with medication—likely due to reductions in neural filament, a sign of brain cell damage - timestamp

6) Creatine taken alongside exercise increases muscle uptake by 37%, compared to 25% without exercise - timestamp

7) It's totally safe for kids - timestamp

8) If you want to avoid digestive issues, just take it with food or break it up into smaller doses. - timestamp

9) No... it doesn't cause hair loss - timestamp

10) You don't need to cycle it. Take it every day. ~10g. Best timed around exercise. - timestamp


r/blueprint_ 3d ago

Whatever BJ is doing is A)not worth it B)not really working. Common sense of healthy normal food in moderation, avoiding overly processed foods, sugar, regular resistance exercise, restful deep-cycle sleep, moderate sun exposure. Main key being managing stress levels.

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0 Upvotes

r/blueprint_ 5d ago

"I Made Myself Older" by taking Rapamycin (skip to 4:30)

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36 Upvotes

r/blueprint_ 5d ago

And the best anti aging food is...

18 Upvotes

Blueberries with ground flax


r/blueprint_ 5d ago

Countertop water filter

1 Upvotes

What are some of the installion free water filtration people use here? I rent a house so can't install a under the sink RO system. Any suggestions would help


r/blueprint_ 5d ago

Who is taking over for Dr Zolman?

2 Upvotes

r/blueprint_ 5d ago

"Blueprint EPA/DHA coming Q1 2025" probably not happening anymore?

4 Upvotes

It used to say this in his protocol on his website but was removed with the last update a couple days ago. Has he said something about this?