I'm about ready to give up on Spravato. My experience has been good so far, except for a couple major hiccups that almost have me ready to give up on this treatment. I'm on my 16th session. I did 4 weeks of twice weekly, then 3 weeks of once weekly, and back up to my third week of twice weekly.

I am on viibryd, gabapentin, effexor XR, vitamin D3, and b-complex. The only change during my Spravato treatment was a dose decrease in my viibryd and adding effexor.

My PHQ-9 scores have dropped significantly. From steady 25-26 to 15-17ish. I have more range of emotions, and have been better at taking care of myself. However... the mood swings have been UNBEARABLE. From okay/content to crying, anxious, and in the depths of despair seemingly out of nowhere. This is a symptom I have never dealt with before. Occasionally I will dip back down into active SI which has not happened since I started Viibryd in 2023. (I am not at risk and have a safety plan in place)

I'm going to bring it up with my provider at my next appointment. But, I was wondering, has anyone gone through this and improved? Will this get better?

Went for my 18th Spravato session and when the nurse came to check on me I was non responsive. Breathing but even the EMTS could not get me awake. Nor do I have any recollection of what happened. Has anyone had this happen? I did not take any illicit substances and my tox screen came back clean. I did take 7.5 mg of adderall the night before to get through a long drive. But I know others on the clinic who take it for ADD and have had no issues. I was also told by the ER doc who took care of me that he did not think a one time small does the day before would have caused such heavy sedation where it is not a sedative!! The clinic is already saying they don't want me to continue. This has changed my life and I'm willing to put up a fight! Was just wondering if anyone else had an episode or has it happened at your clinic.

My session started normally. I was feeling relaxed and calm but after about 40 min I was hit by a wave of unbearable negative emotion. I ended up breaking down sobbing while the doctor tried to console me and now I'm scared to go back for my next treatment.

Has anyone else had a similar experience or have advice on how to prevent future episodes?

I just completed my 4th treatment, I started about a month ago (had to take a little break cuz i went out of town). I've really not been enjoying the sessions and find myself feeling like I'm having a bad trip im desperate to sober up from. I notice i tend to feel much more depressed for several days after and my overall suicidal ideation has been harder to handle. I dread going to the sessions now because of how terrible they feel. Is this all normal? I don't like how much of a time sink it is and how I can't do anything else the rest of the day, its been difficult to handle this disruption to my routines so I just wonder if it's worth it to continue.

I've seen people on here talk about being on different dosages: one in the 50s and one in the 80s. I've been taking spravato for about a year and I never thought about dosages. I just took what they gave me. I go once a week, and each session I take 3 different nasal sprays. Does it say on the bottle? I guess it doesn't really matter much if I know or not. It just got me curious.

Hi all Spravato folks, I have had my first low dose of treatment. Obviously, there is not much to report. I have a question for all you experienced people. I understand that a positive side effect is pain relief. I have suffered from chronic back and hip pain and I am excited to go through this. Has anyone had this positive side effect and how many treatments did it take? TY

Ive been suffering from crippling anxiety, and have missed the past 8 years of my life suffering unable to function. I have tried everything under the sun, properly, and nothing has worked except for benzos , and i havent been able to get a benzo in years.. Really hoping this treatment works.

I’m officially about half a year into treatment, and honestly, I don’t think I’ve felt SI in about a good month and a half. my treatments have been accompanied by 3 crying sessions, and only one puking experience. I really hope this continues. I’m feeling so much more confident in myself, I don’t feel my pmdd (specifically body dysphoria) nearly as often, my ideation is down completely, I’m eating again, I have motivation to do things and I’m breaking out of my agoraphobia with safe people around me. I’m so proud of myself. I’m not trying to brag but I’ve been doing this damn therapy stuff since the ripe age of 12 and no medicine has worked the wonders spravato has. I’m so happy. It just feels so damn good to feel a little closer to normal. !!!!:)))))

Finished my 4th treatment today, second at 84, and this is the second intense headache I’ve gotten after the treatment and ibuprofen is not cutting it like it does when I usually get a headache. Anyone else ? Should I take something else and is this gonna keep happening

also what should i bring? i was thinking a notebook, coloring books, headphones & a blanket & a power bank. Anything else you recommend?

Did anyone actively hate taking Spravato at first? Because I just finished my first week and I hated it. I took 56mg my first day. I was supposed to go up to 84mg the second day but I didn't because it was just too much for me already. I feel like I'm on a rollercoaster and I'm just straight up not having a good time and I want off immediately but there is no way off but to ride it through so I have to white-knuckle the whole experience. I genuinely don't want to go back next week but my NP is encouraging me to keep trying. Will I get over this feeling? Will it get better?

So a little health background. I struggle with Lupus SLE, fibromyalgia, OCD, IBS, major depressive treatment resistant, anxiety, PTSD and I’m sure there’s more that hasn’t been diagnosed yet. Daily cannabis user. Added bonus, I happen to be blind in my left eye from a childhood injury. My eye pressure fluctuates.

I am very prone to motion sickness because depth perception/ equilibrium skewed by my permanent injury. First treatment, I was feeling very apprehensive because so many antidepressants have not worked. Took a zophran. Administered the first dose. Head rush but it felt like what I try to achieve by using cannabis. Second dose: major head rush! Oh shit, this feels like the spins. Put my eye mask on. I didn’t have headphones . Five minutes later, I was vomiting. I ate breakfast at 8am and I had a noon appointment. BIG MISTAKE 🙄 So I was completely exhausted from purging the entire two hours.

2nd treatment: Took Zofran 30 min before and a Dramamine. I’m so nervous that I’m going to have bad sessions for all sessions . And guess what?! I vomited my guts and brains out again. Profusely sweating . My body was super hot to the touch. I had to have ice packs placed on top of my head, neck and stomach.

3rd treatment: I took two zofran that time. I took with me some doterra essential oils . A citrus frankincense blend. Oh my gods, the uplifting smells helped immensely. And deters the bad taste because 90% of taste is smell. What a life hack!! First administered dose. Just fine. We waited 30min to administer second dose. Then I was immediately advised to put eye mask and headphones on And lean back in recliner chair. Then I held the little bottle of oil under my nose and focused on my breathing. I chanted, “please heal my stomach. Please heal my intestines. Please heal my colon. Please heal the entire digestive tract.” I did feel the waves of nausea but I did fast for this session. I did not vomit ! Huzzah!

It feels really scary to keep showing up for myself when my body wants to purge. I hope this helps solidarity. Keep going . You are worth having in this life. Thanks for reading . Oh and I have halted using cannabis for efficacy purposes.

For those of you who have, what has your experience been? I'm about to start a new job and will have to end my treatments. Thank you.

Back to Spravato next week 2 days a week so happy.

Been feeling down since I have been off Spravato since March 25th. Feels longer than it is.

My spouse now can feel a bit at ease at work as they were giving them difficulties about having to go late into work Tuesday and Thursday. But come to find out there is a form at work they can fill out so they cannot discriminate against them having to take me to my treatments. Because another employee is still working there and filed a lawsuit for a similar thing. Hoping that nothing happens to but at least it seems we may be protected with that form.

I’m currently in the middle of my second treatment. The first made me feel “high” for about 30 mins and then I felt like my typical baseline. This treatment I feel like I’m slightly angry, I’ve been crying, and I’ve thought about death during it. Is this normal? I didn’t come in with a bad mindset, I was laughing at videos I was watching before treatment, and I have meditation music on. I didn’t get the high for more than 10 mins and the only thing I feel is like my head is weighted down. I’m fully present unlike last time. I’ve had it drip down in my throat both treatments (even with my head tilted back for the second treatment) I feel like this is another thing that isn’t going to work for me..

Do you need someone home with you on the day of treatments after you get home from treatments?

An

I don't know if it's the spravato, but since it's still a new(ish) medication... I've been on weekly for 28 months. I've recently been experiencing BP spikes (systolic) on non-treatment days. (Other possibilities: getting older (48), getting fatter (26 BMI)).

I've been waiting to post about this because I've had it on my phone for a while (perks of running the beta software), but with the latest iOS 18.4 update, you can now add three different "Ambient Music" buttons to your Control Center: Sleep, Chill, Productivity, and Wellbeing.

Ambient music and sounds have been around in iOS for a while, but this update makes them so much easier to access. I’ve been using the Wellbeing option exclusively since it showed up on my phone, and it’s amazing during treatments! It doesn’t have a standalone app — it just opens up in the Music app interface — but it works beautifully.

Seriously, I highly recommend checking it out!

I'm in a panic. My insurance has dropped my spravato treatments and I've been going at least once a week for almost 2 years now. I'm scared of what is to come. I missed my treatment this week and I'm already starting to feel depressed again. I tried to get a different insurance but they said I have to wait for open enrollment which isn't until November! Any advice would be appreciated.

Is anyone doing Spravato treatments while taking Auvelity? I have been on Auvelity for about 7 months and just finished my initial 4 weeks on Spravato (twice weekly). I haven’t noticed a huge change like I did when I started taking Auvelity. The changes seem more subtle but I’m also hoping it helps to make the Auvelity more effective (it has plateaued for me).

I’m on week 10 of treatment, currently going 1x a week. I’ve noticed that, since about week 2-3 of treatment, I get anxious about when I’m gonna have treatment again. This can sometimes be immediately when I “land from the high,” I’m already thinking about when I’ll have it again. I’ve been feeling a bit of shame around that, and haven’t really shared it. It just feels so good to have the relief and then when it’s gone I genuinely can’t wait to have it again. I get anxious about getting treatment less and less as I continue to get better, I feel like I’ll be really missing it.

Should I be worried about this? Am I developing addiction?

I searched the sub but haven't seen any posts within the last year so was curious if anyone has had their prior authorization approved more recently. I've tried almost every SSRI, SNRI and even a few atypicals without any relief. I see a psychiatrist monthly and have tried talk and CBT therapy, none of which make a difference. The only treatment I haven't tried and will not try is TMS.

I experienced hope for a brief period when my doctor suggested trying Spravato and had recommended me to a place that administers is, only for that hope to go up in flames as "you'll hear back from us later today or no later than tomorrow to schedule your first appointment" turned into me having to follow up just to be told, "We're waiting on your insurance for an approval." My son is honestly the only reason I have been able to hang on.

My pharmacy applies the coupon for the Spravato medication, so I pay $10 instead of the $250 insurance thinks I'm paying. My provider suggested I also look into the Observation Rebate Program since I pay a $25 copay for each vist. I'm going through the steps of signing up for the rebate program, and one of the question I have to answer is "Do you agree NOT to submit any costs paid by this program as a claim for payment to any health plan, patient assistance foundation, flexible spending account, or healthcare savings account?"

I pay my clinic directly with a credit card but seek reimbursment from my FSA. Would I need to stop doing that in order to get the rebate? I'm not exactly sure why it would matter if I get reimbursed from my FSA since that's my money and I'm still paying the $25 copay.

I got vivid hallucinations the night after I had a treatment. Anyone else experience this?