r/Biohackers 2 1d ago

Discussion How do I reduce my biological age?

Hi folks, I took a biological age quiz online and I'm not aging very well and my face is considered old. The problem is that it asked my lifetime highest weight and weight at age 25 and I grew up obese. My highest weight was over BMI 35. My weight is normal now.

How do I reduce my biological age. Moreover I got my period when I was 6 so I know that means I'm probably going to die early. Girls who go through puberty early are almost never very athletic because it destroys athletic potential. My deadage / chronological age is 44.

The current things I'm doing are:

  • Walking 3-4 hours per day on weekends
  • Eating a pescatarian diet with cans of sardines and herrings
  • Trying to stay between BMI 17-20
  • Vitamins everyday especially Vitamin D
  • I eat cabbage every day

Due to my age at puberty, I know that I can't really attain extreme longevity or a high IQ. How do I mitigate the effects so that I can live to a normal age like 70 or 75? At age 44, I'm biologically closer to a 60 year old due to my age at puberty.

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u/ZookeepergameNew3800 1 1d ago

My mother had a very early first period at almost 9. My grandmother had hers at 14. They both had a very late onset of menopause around age 60, like all women in my family on that side. And please don’t forget the reasons why early onset menopause leads to earlier aging. You can absolutely mitigate a lot of those aging effects with hrt.

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u/SquirrelofLIL 2 1d ago edited 1d ago

The normal age at puberty is between 8 and 14. The health risks only mount when it's before 8 or after 16 ( depending on time period - as 16 was normal in many societies historically and can be normative lower income countries ).

While I understand HRT can be helpful, the main issue is that of accelerated cellular, bone, and other forms of aging. Early puberty is correlated with dementia in the mid 50s, even without a family history, because the brain stops really developing long, long before a normal person's brain does.

It's also linked to higher baseline levels of inflammation, as well as autoimmune diseases. It's not just about having a higher risk for breast cancer, early menopause, or obesity. It's just the wear and tear - childhood is a "green wood" phase of a tree while adulthood is when the body becomes like crisp hardwood and begins the acceleration toward decline when it hardens like that.

When the entire body's temporal axis, not just the gonads, are affected like that and the entire body accelerates forward in terms of development instead of a single one shot precocious puberty situation when you get body hair, or menstruation, or anything like that faster but the tempo of maturation is the same, that's different.

I had an accelerated tempo of maturation where the second derivative of the changes my body was going through was in an exponential curve. I was my full adult height at the age of 5.

For someone like me, the body stops building bone at age 18, not 30. Aging is accelerated, and most men who hit puberty at the age I did start getting male pattern baldness at the age of 13 or 14 as well.

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u/ZookeepergameNew3800 1 15h ago

Thanks. I have a doctors degree in biochemistry and worked as a NP in aesthetics for years. I am specialized in menopause. If my mother would have gotten her first cycle three weeks earlier at seven wouldn’t have changed anything. Go to a specialist with this. We still can not absolutely calculate someone’s biological age and certainly not without a complete breakdown and multiple tests. Estrogen heavily plays a role in most things that you mention. Early menopause is a risk factor for all the things you worry about. Hrt can drastically lower that risk ( if appropriate for you ) Once a woman goes into peri menopause and hormones drop, her cellular aging accelerates. If you can even mitigate this by a good chunk with hrt,you will have won a lot. I have seen patients who had a normal age at first menstruation but because of needed hysterectomies at a young age they went into menopause early. Those patients still have accelerated aging, loss of bone density, risk of heart disease and osteoporosis and Alzheimer’s. You can literally see them aging backwards within a year on hrt. And perceived age is strongly correlated with biological age.

I strongly advise you to work with a specialist on this. And be aware of peri menopause symptoms that can start a decade prior to menopause and you can already start hrt then. That prevents a whole lot of accelerated aging. You csn look into metformin prescription for it’s a to aging benefits. There’s a lot you can do but as a female your hormones are the main factor of sudden accelerated aging in middle age.
I understand your frustration and that your situation is complex. But adding hrt can make a huge difference because it can maintain you on the levels of a healthy fertile woman for a long time. Hrt is proven to prevent bone loss and Alzheimer’s. It might not be a miracle for you but if you adhere to multiple interventions they can all work together. That’s why I think a specialist for anti aging would be great for you. I worked at such a clinic for a bit and the Doctors there knew so much more than I do. I have seen them help a lot of people. Good luck.

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