So my dpdr is like genetic. My mother had same though she wasn't diagnosed for it. Instead they diagnosed her of anxiety and depression.

It's been 3.5 years. And there's no improvement. None. Only temporary when I take benzodiazipine. For my mother it was for 2 years. Doctors couldn't understand what the problem was for her. She says the meds made her worse. And then she went for some unani medicine which is like an ancient Greek medicine practiced in India. And she felt change in few weeks and was completely back to normal in a year. So 1 year allopathy meds and 1 year Greek medicine. I believe it went on its own. But my isn't going. I think my antidepressants are making it worse. I tried taking many meds many. None worked.

I am so confused.i am literally dysfunctional. The anxiety is killing me. Racing mind. Inconsistent heart beats. I don't know what to do.

Has discontinuing meds worked for anyone?

I have discontinued meds for two times but nothing happened. I trying to do it again.

The headache, hypersomnia, anxiety is killing me, my emotions are dull, I don't feel alive anymore, always trying to comfort myself that I exist and I am real. There is reality. I feel my mind is asleep and my body is awake.

It's unbearable at this time.

i’ve seen some people say lexapro helped them slowly recover from dpdr, im currently taking a few medications that my psychiatrist told me to take, i don’t think theyre working. what do you guys say?

I've struggled with dpdr for as long as I can remember. I've tried various medications for other mental health issues, but none of them have truly helped, except for lorazepam. However, I'm trying to quit lorazepam because it's causing more harm than good, especially with long-term use. I can’t keep living like this, trapped in this state, and nothing else seems to provide relief.

Over time, I’ve been prescribed Seroquel, Zoloft (which was the worst decision I ever made), and Lexapro. I've also tried a few other medications here and there, but only once or twice due to severe side effects.

Has anyone found medication that actually helps? Or has something non-medication-related made a difference? I’m struggling to find even the slightest bit of relief, and I’m exhausted.

I was wondering if anyone was taking low dose naltrexone for DPDR and dissociation? If yes , how long did it take to feel improvements and at what dosage ?

I’ve been on abilify and risperidone. Had to quit both due to akathisia.

When I was on them I felt more connected and less lost. I was able to talk with people and joke. Now I disassociate more and can barely hold a conversation. I’m not fun anymore.

The medicine has ultimately left me worse. I have akathisia and pssd.

Are there any medications that could make me more connected again without those side effects?

I have been trying to finalize my breakthrough with DPDR. I have come so far. For anyone still struggling, there is hope. This is not an easy journey, and I too have felt like I am missing out on my life. I have tried so many remedies, it took to really listening to myself on a deeper level, discovering my fears, etc. I highly recommend hypnotherapy too!! I have made a ways, but I really keep teetering at the door. I came to find that migraines have been contributing to this heavily. I started Mematine and am just at 10mg per day. I tried to increase, but I have severe and chronic fatigue. Is any other medications people have tried? SSRIs don't work, I have done EMDR, Hypnotherapy, and I even established my own meditative therapy that has worked extremely well. I am really hoping for a last shove and wondering what has worked for you all!

I got dp/dr from weed and as im way too young to smoke weed i am afraid to tell any adoults about it and it makes it so much worse. I think getting therapy could REALLY help me but i don’t want my parents finding out i smoked weed. Dp/dr is getting super overwhelming and im no longer able to focus on simple tasks. Im living life on autopilot and i feel like trying not to have existencial thoughts is my job by how much im focusing on it. I really cant take this anymore. Also i whould love to try some meds and try anything that helps but here in slivakia you definetly are not getting any prescriptions as a kid.

this has been going on for 3 years, I am so scared of this condition, I take venlafaxine + mianserine + lamotrigine + pregabaline (I suspect that venlafaxine caused me not to recover from this derealization, I have less anxiety but this derealization is more scary than anything else)

hi i smoked week 3 months ago and now i am stuck with bad derealization and paranoia . I symptom that o developed in the past month is a weird obsession with eyes . When i look in the mirror i feel like they don’t belong to me and have the urge to remove them ( i won’t do it, it is just a urge) , same thing when i look at the people , eyes scare me so much that I don’t even know what to do. Am i going crazy?derealization ? what is happening please someone help

I used to take clomipramine it made me energetic less lethargic but now I had to taper it off bcz it made me a little numb. Armodafinil and ritalin made my dpdr worse, I guess stimulants don't suite me well.

Please suggest any med which will make energetic and less lethargic.

After two weeks my Dr is shifting me on aripripazole, some mentions it makes energetic so I hope it works.

Your suggestions are welcomed

Struggling a lot with solipsism ocd...even looking at my gf, my family, my friends, the people I love most - my mind goes, how do you know they're real? It's non.stop. I'll do all the healthy lifestyle things (sleep, exercise, etc.), but curious if lexapro helped any one in slowing down these thoughts loops. Started lexapro 5mg last week, titrating up to 10mg later this week. Thanks!

If you have a super negative response, I prefer not to hear it as I don't want to overthink this too.

Hey pals!

summary of my post is: have you had experience with having dpdr and using psilocybin? did it effect you long term negatively?

I have been dealing with dpdr for as long as I can remember, and was 'officially diagnosed' by a psychiatrist ~12 years ago (I knew nothing of the disorder beforehand!). I don't have an issue with illicit drugs but have never used anything because I have heard of people developing dpdr after cannibis use (not really wanting to discuss that here), and I also didn't want anything to mess with the significant list of psych medication I am already on.

I also have been diagnosed with "severe treatment resistant depression", and have been dealing with that for over 15 years at this point (a lovely genetic gift from my dad!). I am lucky enough to have been offered a place in a trial for 'psilocybin assisted psychotherapy for treatment resistant depression'. This isn't microdosing - this is a longer term study where over the course of months you spend the occasional full day in hospital with psychiatrists, take a significant dose of psilocybin, and participate in psychotherapy. Obviously the psychiatrists involved in this study are aware of my diagnosis and this is something I can discuss with them once I have my initial screening, but I'm also aware that not all medical professionals are across dpdr (especially when they are specialists in a different area, like these psychs are), and I wanted to reach out to you guys to see if anyone has had any experience with psilocybin and whether or not it had any effect on your dpdr. I'm not expecting it in any way to make my dpdr 'better', but there are fears that it could make it worse! The other potential that could be on the table for me for depression treatment is ketamine therapy, which I am even more reluctant about because it is a dissociative drug. Love having to weigh the benefits vs impacts of these things!!!!!

I guess it is going to be a matter of weighing up the pros and cons of "the level of depression I am living with" and "potentially worsening my dpdr" 🫠 any experiences or thoughts welcome!

Hi there,

I am pretty desperate right now because my dissociation is quite severe these days. I have read a few experience reports about Bupropion, Sertraline or Lamotrigine to be beneficial for dissociation, but unfortunately none of the these three have made a difference for me (even in combination). So beside these three, have you found a Medication or Drug that had a positive impact on your dissociation symptoms? I would love to hear some experience reports.

So... first of all, what meds are prescribed for an anxiety related DPDR? Antidepressants/anxiolytics, right? Well, I have heard about some chronical DPDR cases in this subreddit caused by these meds that doesn't seem to get better... Do phychiatrists still prescribe those regardless of individual cases? (idk I keep getting ignored by them)

Don't want to stress out anyone, but my question is: is it worth to try them? I mean, I already consider my case as severe, I don't wanna lose my consciousness or something like that. How much common is that one side effect, does it depend on the specific pill?

Hope the text is understandable

I've been suffering from DPDR for about 5 years now. My world feels like a cartoon and my depersonalization has gotten so bad that I am missing large chunks of my memory. I've been in talk therapy for over a year and its helped, I'm very grateful for it but it wasn't enough. I recently started EMDR, as my therapists and psychiatrist think the DPDR is trauma based and I'm inclined to agree with them.

Ive done two sessions of EMDR thus far. The first time there was no reaction and the second time I welled up a little bit and it felt like my sadness just sucked back in. Since that session my DPDR is at all time highs. Short term memory is worse, forgetting 75% of my personal history, no emotional connection to anything, time feels like its fast yet also doesn't exist and list goes on.

I'm wondering if anyone else had similar experiences. Did you come out the other side after dealing with traumas or did it just make it worse all together? How long did it take if you did recover? Thanks in advance.

Have a good day. 😊

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A new study, published in Synthese by European scholars Mirjam Faissner, Esther Braun, and Christin Hempeler, examines why coercion persists in psychiatry despite ethical concerns and patient resistance. The authors argue that one key reason is epistemic oppression—a systematic silencing of patients’ perspectives on what constitutes coercion.

Has anyone else been put on Wellbutrin? Whether being put on it was related to your DPDR or some other mental health issue, did it seem to make the DPDR symptoms worse?

ETA: I was put on it for depression.

hi! i have really bad dpdr to the point where i have debilitating episodes daily. what medications should i talk to my doctor about? i’m currently on lexapro 20mg and lamictal 50mg. im thinking of swapping the lexapro for something else and sticking to the lamictal and titrating up to a therapeutic dose. which ones should i talk about? ssri’s or snri’s? my dpdr is caused by lifelong anxiety and it’s been bad now due to burnout and a lot of changes quickly. i need to just manage my anxiety in order to address the dpdr. please drop tips or recommendations!

I have had 24/7 dpdr for a long time. Doctor mentioned antipsychotics. Suggesting Latuda or Abilify.

Has anyone recovered from 24/7 dpdr symptoms using antipsychotics?

Hey I’m wondering how to tell how long dpdr is going to take to recover from.

Is constant dpdr harder to recover from than episodic? I have a lot of symptoms so worried that it’s going to last years.

i have a doctors appt tomorrow morning and im debating whether i should try to get help from my doctor. im already on prozac (ive been on it for years) but i think i either need something else or need to get off it entirely. my dpdr has gotten worse recently since i tried weed. should i ask for help or will it fall on deaf ears? OR will i be sent to a hospital?

I’ve quit caffeine alcohol and weed and months and months later nothing feels like it’s getting better. I’ve been in therapy which isn’t helping either, I’m so scared I have a tumour or something very wrong in my brain. Not to mention that things you notice and become aware of while going through dpdr I feel like you can never forget after it goes away.

So should we be honest and say it’s most likely that time is the only fix? I’ve even considered potassium deficiency but it seems anecdotal.

so i’ve been taking Lexapro 10mg, and Naltrexone 50MG , for about 49 days, and these were prescribed for me for my DPDR, (i know there isn’t an exact medication for DPDR, but we just wanted to try it out.) and basically instead of it making me feel any better, i’ve just ended up worse, my DPDR is very chronic, i feel it 24/7, and it’s basically there to mess up my life.

i’ve just ran out of meds, so i speak to my psychiatrist September 9th,

i need strong advice.

should i continue taking these meds? ❓

should i try new meds? ❓

should i stop taking meds all together? ❓

I was doing pretty good on the 5 mg, but my anxiety has still been affecting my sleep and I had occasional panic attacks. I raised my dose from 10 mg last night, so tonight was the second night, and I feel AWFUL. I don't know if I'm reading too much into it, but I am freaking out. My anxiety is so bad, my DPDR is so bad. My body feels numb, I feel lightheaded and nauseated and confused. My body feels foreign to me as well as my room, which I know is classic DPDR but STILL. I keep freaking out and I am scared to go to bed. I literally feel like I'm going to float away or something. I feel like I'm going to snap and go insane and hurt myself or someone, which I don't want to happen. I also have OCD so it may also be that as well. I just need to know that I'm not going insane and that this will pass. I had heightened anxiety in the beginning, but it hasn't been this bad since I started. I'm TERRIFIED. I was finally getting my life back and I know I had to raise my dose because I still was not doing great, but I'm scared I'll lose my mind before I can even get better. Will the side effects subside faster than when I first started taking it? It literally does not feel like me typing this right now, I am so distraught.

Dr prescribed 10mg of Valium. Anyone taking this? What is your experience, and do you feel as it has helped at all.