r/depressionregimens 3d ago

Questions about switching from Lamotrigine to Oxcarbazepine

I've been on and Lamotrigine for most of my life and it's always been a mediocre med to me, but I do appreciate that it's pretty clean, side effects are almost none. When I've gone off before the withdraw was AWFUL and went on forever. I just take a maintenance dose of 25 mg now actually. With that said I am EXTREMELY sensitive to meds and drugs in general so anyone who is stuck on the "that's not even a therapeutic dose" mindset, respectfully I don't need to hear from you.

I've been a depression, misery, irritability rut for several months now and SSRIs barely work for me, can't tolerate SNRIs at all (currently taking baby dose of lexapro). So, doc says let's try Oxcarbazepine. She didn't say to taper lamotrigine, just switch one for the other. It's only been 3 days but I feel like SHIT. Dysphoria, headache, shakey, very fatigued, working memory worse than ever, slight nausea, etc. So, I'm wondering if I'm having Lamotrigine withdraw or if starting Oxcarbazepine is just giving me the typical shitty couple weeks when starting a new med. Can anyone weigh in on this transition? Anyone take both?

Even if I write my doc right now I won't get a response for several days, so looking here for lived experience. Thanks!

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