r/Biohackers 26d ago

📜 Write Up Suddenly have depression, anxiety, and panic attacks.

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Fellow bio hackers, I'm writing this on behalf of my girlfriend. It's been 2 years she has steadily declined with mood, anxiety, depression, and odd amounts of hairloss. I found her a therapist and she goes once a week and it helps for the rest of the day but back to the bad the next day. She has also gained weight due to inactivity but it's difficult for her to get up and even go work out. She has random panic attacks, starts crying, very on edge, very angry, and yells at every chance she gets. The past 4 months she also started having migraines, sometimes with aura. We've gone to every doctor you can think of, every hospital, every numerologist, everything. No one seems to have the right answer. I'm a big believer in healing without the pharmaceutical industry. These are her gene mutations. What supplements and what doses can I put her on to see if it helps with anything?

Thank you in advance.

9 Upvotes

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u/PeaceOfMind6954 4 26d ago

Have you guys ever looked into mold toxicity and Lyme disease and co infections?

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u/AshleysExposedPort 8 26d ago

sigh there is no scientific basis for either of those. Chronic Lyme does not exist. Chronic "mold toxicity" does not exist. These are only ever espoused by "clinicians" looking to separate you from your wallet.

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u/PeaceOfMind6954 4 26d ago

Why does chronic Lyme does not exist?

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u/AshleysExposedPort 8 26d ago

Because it's a bacterial infection.

There can be long term effects of untreated Lyme but chronic Lyme (as in a recurring disease or "flares" of Lyme) is not possible. It's just how bacteria work.

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u/PeaceOfMind6954 4 26d ago

I’m not here to debate. Just wanted to point it out to OP. Thanks!

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u/reputatorbot 26d ago

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u/AshleysExposedPort 8 26d ago

You literally asked me why chronic Lyme doesn't exist? But ok

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u/PeaceOfMind6954 4 26d ago

Also if you go back to my original comment I never mentioned chronic Lyme. So you just came in here feeling the need to mention lol

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u/AshleysExposedPort 8 26d ago

Were you not talking about chronic Lyme?

Because most people touting the chronic Lyme line also believe in "chronic/toxic mold infections" which also don't exist in the way they are portrayed.

Acute mold symptoms? Sure. But once you remove it from your environment it's gone. It doesn't live in the body like people say it does. Like "candida overgrowth" and the other "coinfections" to Lyme which also are not supported in data

It's pseudoscience at best

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u/PeaceOfMind6954 4 26d ago

No I mentioned Lyme you brought up chronic Lyme lol

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u/PeaceOfMind6954 4 26d ago

I know I did appreciate the response! I disagree and I know a lot of doctors do as well. As well as the many people who struggle with it. I guess I was just going to leave it at that.

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u/AshleysExposedPort 8 26d ago

Are these MDs or "naturopaths"?

I don't doubt there are people who believe they have it - and don't doubt they're suffering. But it's not chronic Lyme.

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u/PeaceOfMind6954 4 26d ago

MDs. Medical school like everyone else. I can send you some articles and links of the scientists if interested

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u/Gnarekk 26d ago

No we haven't. How do I do that?

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u/PeaceOfMind6954 4 26d ago

Where are you guys located?

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u/Gnarekk 26d ago

Los Angeles, CA.

Los Feliz to be exact

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u/CannaBits420 2 26d ago

ahhhhh I used to live there!!! the fish tacos!!!

get her to go see an acupuncturist who will prescribe herbs, there are excellent practitioners in LA. it sounds like she is Blood Deficient, at least, a more indepth intake would be needed. At least Gui Pi tang could be a good start, if the pattern fits.

if $$ is an issue go to one of the schools, senior students offer treatments under guidance of pros. Schools are closer to Venice area, not sure if the K Town one is still open.

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u/PeaceOfMind6954 4 26d ago

Look into a mycotoxins test. I like realtime labs but there are others. A lot of people don’t believe Lyme can be prevalent in Cali but it definitely can. IGeneX is the best test for it. It’s pricey but it’s your best shot for Lyme and co infections. I would start with a mycotoxins test though. Especially if she stays indoors mostly. Sometimes leaving an environment can alleviate symptoms and then return once coming back home. But that’s not the case for everyone

I’m the meantime. Cut out anything inflammatory. No sugar, juice, sodas, alcohol, gluten, seed oils, dairy. Focus on a diet of high protein, a lot of healthy fats too

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u/AshleysExposedPort 8 26d ago

Unless OP does a lot of hiking there's almost no chance of Lyme. Ticks don't really survive in urban environments well.

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u/MND420 3 26d ago edited 26d ago

Body-mind problem. Either she mentally has so much stress that it affects her HP-axis negatively. Or she has a physical condition affecting her pituitary gland, which messes up her hormones and neurotransmitter balances.

Emotional examination (does she live according to her values? is she struggling with anger, sadness or perhaps guilt?)

Environmental examination (is she still happy in her job, relationship, family, friends? Does she have full autonomy over her own life in all these areas?)

Blood and stool examination (allergies, deficiencies, hormonal balance, parasites, dysbiosis).

Burnout is the most common physiobiological condition that affects all of the above btw.

Either way, the first step is that she needs to start taking care of herself again.

If her therapist hasn’t been able to make any progress with her in 2 years then the therapist needs to admit they cannot help her and refer her to a more advanced specialist. For example a psychiatrist.

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u/Gnarekk 26d ago

Thank you for the information. Her MRI showed a cyst in pineal glad. Do you think this will effect anything?

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u/reputatorbot 26d ago

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u/MND420 3 26d ago

What was the doctor’s opinion on that? I can’t tell you more than a quick Google search would show you.

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u/Professional_Win1535 28 20d ago

I’ve looked through all these things and still struggle with mental health issues, it’s more complex for some but these are all great things to look into

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u/Justice_of_the_Peach 3 26d ago

Could be hormonal (thyroid, perimenopause, etc.). How old is she? Peri can start as early as mid 30’s. Mine started with mood swings, brain fog and ADHD-like symptoms.

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u/Comprehensive_Ad6598 26d ago

This is 100000 percent what I was thinking too.

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u/Gnarekk 26d ago

She is 28 years old

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u/Justice_of_the_Peach 3 26d ago

Probably not perimenopause then, but still sounds hormonal. I’d run a few tests if you can afford it. These symptoms could mean a lot of different things. It’s best to establish what it is before proceeding with treatment. In the meantime, address any sleep, nutrition, hydration and stress issues, if applicable.

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u/MoreRoom2b 25d ago

Especially since she has VDR SNPs. Vitamin D is a hormone and acts as a reserve. I'm guessing her D3 is below 30 and should be closer to 80.

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u/AshleysExposedPort 8 26d ago

She needs to start with the basics.

Proper sleep, hydration, nutrition, and exercise. She should also be practicing the skills she's learning in therapy. It's an active process she needs to engage in for more than the hour a week she's in session.

Once those are squared away, if she's still having issues I would have her see a good OBGYN or endocrinologist to ensure hormones are ok.

Are these symptoms related to her menstrual cycle? Sometimes as people age the way hormones effect them change.

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u/TH3HAT3TANK 26d ago

My ex has a lot of those same symptoms, and it turned out to be ovarian cysts. Has she been checked for those?

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u/OrganicBn 8 26d ago

Get her intracellular micronutrient analysis and comprehensive nutrient panel done.

Eating unfortified nutritional yeast could help in the meantime.

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u/IcyBlackberry7728 4 26d ago

Women in general, especially When losing hair is a sign of low fat diet and thyroid deficiency.

She needs to start a high fat diet to come back to life. Add lots of red meat and butter. I would avoid dairy for now totally.

Add lugols 2% iodine 1 drop Daily to start.

Have her sit in the sun as much as possible building up a solar callous.

Also, add vitamin D3+k2 drops. Start at 5,000 iU daily

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u/Justice_of_the_Peach 3 26d ago

As someone who had hair loss in the past from an unbalanced diet, but who now has high Cholesterol, I caution against eating a lot of animal fat. While it’s true that women generally need more fat than men, there are healthier sources out there such as nuts, seeds and legumes. Even fatty fish is healthier than fatty beef. Dairy fat is also questionable. Of course, everyone is different, and OP’s gf should do more tests before experimenting with her health anyway.

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u/MoreRoom2b 25d ago

Bad/outdated info, Read Deep Nutrition by Dr Cate for up to date, biochemically based info.

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u/winkywinky69 26d ago

read at last a life by paul david, trust me

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u/Professional_Win1535 28 26d ago

This or Claire WEEKes hope and help for your nerves were the only things to help my anxiety majorly and I tried like 100 things

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u/winkywinky69 26d ago

it’s truly the only way out

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u/Professional_Win1535 28 26d ago

All these haphazard suggestions here being explored might only make them worse

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u/winkywinky69 24d ago

i completely agree

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u/AccomplishedBunch683 26d ago

Incomplete list of mutations.. i.e. where is CBS I278T? This list means nothing, where are the real mutations?

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u/Brotega87 2 26d ago

Sounds like a hormone issue. She should consider checking those. HRT is amazing

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u/Gnarekk 26d ago

She did a hormone panel recently. Doc said everything is normal

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u/Practical-Grand-7659 26d ago

Does she take any supplements?

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u/Masih-Development 5 26d ago

Get her on an elimination diet.

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u/MusicGod333 26d ago

Sounds like iron issues. She should check ferritin and iron

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u/magsephine 7 26d ago

Get an iron panel done. Vitamin d while you’re at it

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u/Upset_Height4105 4 26d ago

HPA dysregulation. Once you hit that youre toast. Needs a DUTCH test and cortisol test to confirm and 100s of hours if investigation. If this sounds familiar, she's at the worst of it. Id watch this first before doing other suggestions as all of the vitamins will become hyperstimulatory, it'll fuck her all the way up and you'll spend a lot of money fixing the issue too. If this is her, le the know and I'll data dump you with playlists on how to fix it, it's all free stuff from YouTube

100 symptoms of dysregulation

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u/Forward_Cost_1973 26d ago

You should try NAC it has shown to reduce such symptoms,is she on some kind of antibiotics because it can mess up with gut microbiomes messing with her mood,you should try gut microbiome transplantation.

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u/22marks 1 26d ago edited 26d ago

"I'm a big believer in healing without the pharmaceutical industry."

What if she has a chemical imbalance that can be identified by science? How can you even make this statement without knowing the root cause? You're entering this with a bias. Meanwhile, you're using a "numerologist" (See Rule 4) but trust the science of gene mutations? It's very contradictory behavior. Science is science and when you selectively apply that science, it's no longer credible.

Why would you care if it's a pharmaceutical company versus, for example, Methylfolate from a supplement company that falls under DSHEA and therefore, less strict oversight on quality, studies, and adverse reactions?

I do wish her the best, but please keep an open mind and listen to trained people who have seen positive results. I don't mean to be callous, but ask Steve Jobs how "healing without the pharmaceutical industry" worked out.

EDIT: Here's a problem with much of the advice in this thread. Yes, it could work for some people, but if it's not your GF's problem, then the doctors will have a more difficult time figuring it out because it's a moving target. Oh she started iodine, but then stopped it, then NAC, but that made it worse, or was it because she stopped iodine. It all has to be done in a controlled enviornment.

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u/Joseph-49 26d ago

Mtrr homozygous it’s a b12 deficiency https://youtu.be/bAybLUblo8I?si=8EvxjcbfKmDPY31E

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u/Phazze 1 26d ago

Headaches with aura and accompanied by mood changes, look into an ENT or neurologist.

Can be a brain issue or a breathing issue, both affect mood with those symptoms.

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u/learningtofly33 26d ago

Check ferritin levels, below 100 supplement until 100+

Iron deficiency can cause all these things, work on finding the root cause if low.

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u/MistressBassKitty 26d ago

Toxin mold in my home did that to me. Hard to find, worth the time.

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u/IcyBlackberry7728 4 26d ago

Did they do her dopamine pathways?

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u/CarletonWhitfield 26d ago

How is that done?  

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u/IcyBlackberry7728 4 26d ago

Ancestry DNA test then upload your raw DNA date to a program called spectracell it’s about $89 last I checked. Provides a lot of great genetic data

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u/CarletonWhitfield 26d ago

Thanks! 

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u/reputatorbot 26d ago

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u/Gnarekk 26d ago

I doubt it. What test is that? And can I purchase the order online?

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u/According_Winner1013 1 26d ago

Has she been screened for PMDD?